Stem cell therapy for dogs

 In the previous entry titled “Run like wind again;Palette’s limping story“, I wrote that when she was about 1 year old, we noticed that our dog “Palette” was not putting much weight one one of her hind legs and, started limping so,we took her to the local vet.

 There,the vet took her leg’s X-ray and he has performed test called “drawer sign test”:it is to see the abnormal function of the legs. What he did was manipulating her leg to see if she had any
abnormal sliding motion.

 He showed us the X-ray picture and told us she
might have torn ligament considering she had drawer sign when he tested
it. So, we were off to see Orthopedic Special Vet.

 At the Orthopedic Special Vet office, looking at the x-ray picture, the orto vet also thought it must be tore ligament problem,which later turned out she had perfect ligament and, nothing was wrong when the ortho vet took a look inside her leg. Therefore, the ortho vet just closed her leg up, and she was still  limping after the surgery which went through for nothing. Ortho vet had no idea what caused the limping if it were not the ligament tore.

 Why Palette was limping is still the mystery to us.

 It might be just the sharp turns she does sometimes while zoomie time might have put the stress on her joint or maybe slipped on slippery floors and pulled the muscle, or maybe the particular day’s walkie was lot longer than the usual and might have caused limping.

 What helped her was tablet that contained glucosamine/chondroitin/NZ green lipped mussel etc..and in short amount of time, her limping went away and she started enjoyed her favorite fetch ball/Frisbee game again.

 She is not on the tablet anymore. However, since she has history of limping, I make sure to give natural source of glucosamine rich treats or food regularly.

 With treats,I give trachea,poultry feet, and gullet treats regularly. You can find those at Yassy’s Gourmet Dog Kitchen;trachea  (Beef,Lamb,and Buffalo) , poultry feet (Chicken, Duck), and gullet (Beef,Lamb).

 In addition,since Palette is on fresh food diet a.k.a. raw diet, I also feed fresh poultry feet (Chicken,Duck) and Beef Gullet with her regular diet menu regularly.

 Before the “surgery that improved nothing”, we talked about many surgery options such as TPLO,which ortho vet will cut the bone to make it flatten tip, and secure bones with screws. However, with stumpy Corgi like Palette’s size,the ortho vet thought that the method and tools they use for TPLO would not
match well.

 So, what she recommended was to do non screw method, which
involve suture to secure the bone, and suture itself would dissolve into
body overtime.

 There were also possibility that if we restricted her activity for long time and see if she would recover naturally.

 Watching Palette limping was painful
for us, and especially when we know she loves running around the house
or loves to compete running to house on walks with me. So,we chose to go with
non invasive surgery with suture and, Palette went under the surgery.

 Recently, I came across quite interesting article on stem cell therapy that has been used for treating arthritis,fractures,ligament injuries and so forth.

What is stem cell therapy?

 According to the article written by Rona Sherebrin DVM,CVA, stem cell therapy is done by collecting the small amount of fat in the animal and then, isolating the stem cells,whose job is to produce the correct types of cells to repair the damage, from an animal’s own tissue and injecting them back into their own damaged tissue to heal.

 When the stem cells are isolated, they are concentrated and those concentrated stem cells will be injected into the damaged tissue and it helps heal faster.

 She writes that fat tissue contains enough stem cells to make collection and isolation.

 I feel that since there is not cutting the bones or screws involved, it seems less invasive and this might be good addition as options for joint injuries surgery methods.

 Plus, stem cells that will be injected will be from their own, so as Rona writes, vets do not have to worry about tissues being rejected by body and no need to use the anti-rejection drugs.

NSAIDs (Non Steroidal Anti-inflammation drugs)

 If your dogs have/had joint problems, you maybe familiar with the word “NASAID”.

 Popular drug in the Non Steroidal Anti inflammation drugs category being Remadyl.

How NASAID drugs works

 According to Dogs naturally magazine article, NASAID drugs alleviates the pains and inflammation caused by dogs’ arthritis. The NASAID drugs can do that by inhibiting the pro-inflammatory enzyme prostaglandin.

 When NASAID inhibit the pro-inflammatory enzyme “prostaglandin”, it also suppress the other enzyme’s other functions.

 The article says NASAID can cause ulcer,because the pro-inflammatory enzyme “prostaglandin” is important components in the protective stomach lining and upper intestine.

** Signs to look for for ulcer are vomiting,change in appetite, blood in the stool

 Pro-inflammatory enzyme “prostaglandin” also plays important roles for kidneys,because “prostaglandin” will make sure that the enough blood was reached to the kidneys.

 The article says that if there were enough NASAID in the dog’s system, it can reduce the blood flow to kidneys.

 NASAID is well known for the side effects on liver function,as well.

 If your dogs will be on NASAID drugs for long period of times, it is best for your dogs to have their blood tested for liver enzyme levels regularly.

 In the article, vet Wayne Randlph says he test the dogs’ blood before and after NASAID for liver and kidney.

 I think that checking the organs’ function before and after might be the better ideas if you know your dogs will be on it long period of time.

 To relief the joint pain after surgery, Palette was on tramadol. Tramadol is not NASAID and it is a pain relief medication,and dogs can be on it for long period of times.

 I am not a vet,and I am not sure if there were any type of dogs that should not get tramadol as pain relief or dogs that should not have tramadol as medication because of the other medication that are already being prescribed to. So, ask your vet whether tramadol can be the safe alternative to NASAID drugs for your dogs’ pain relief.

 To read the full article at dogs naturally magazine website,please click here.
 
 As I wrote above, if dogs had limping problems, just like Palette’s case, vet often times prescribes some sort of pain reliever.

 When you think about it, pain relief can help your dogs to do their normal activities they enjoy, but the drug can be suppressing the pro-inflammatory enzyme with NASAID drugs,for example, thus dogs would not be without constant joint problems.

 With stem cell therapy, Rona writes that it rebuilds the healthy tissue so joint can improve.

 In some cases like below, Rona says to correct it with surgery first before stem cell therapy.

** dogs with unstable joint (ACL; anterior cruciate rupture)

** if there were bones/cartilage fragments inside the joints

 She also write that for dogs with cancers, dogs with severe infections, and topical wounds, stem cell therapy is not recommended.

 To read the full article written by Roma Sherebrin,DVM,CVA, please click here.

 The company “Vet Stem” ,where vets send small amount of fat collected from animals so they can isolate the stem cells, is now testing stem cells to treat kidney disease in cats, liver disease in dogs.

 You can see the stem cell therapy youtube video below.

Stem cell therapy for dogs

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 Stem cell therapy article at time magazine here ; German Shepherd “Blue” with Hip Dysplasia

 Stem cell therapy article at USA today here ; German Shephered “Maggie” with Arthritis

 Dogs be dogs… That is what makes me smile.

 
I love seeing Palette running around with big grin on her face, roll on something in our yard with big,big smile on her face, and I have fun when she brings her squeaky eggs toys for me to throw for her with excitement “woof” with small nubs moving left to right…

What are your thoughts on stem cell therapy?


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Aug 23, 2011 | 0 | Uncategorized

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